Precision Medicine requires an ever growing Biomedical BigData reference. This growth is particularly striking for pathologies with a genomic basis, like Cancer. Accordingly, NIH/NCI has spearheaded the establishment of interoperable multi-petabyte sized Genomic Data Commons as a data ecosystem that the scientific community, including the citizen scientist, can populate with analytical applications. The goal of this project is to explore this new data-rich landscape by developing nimble Web Applications (Apps) that help find novel associations between genomic features and cancer phenotypes.